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1

Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation

Garn, Holger, Bahn, Sabine, Baune, Bernhard T., Binder, Elisabeth B., Bisgaard, Hans, Chatila, Talal A., Chavakis, Triantafyllos, Culmsee, Carsten, Dannlowski, Udo, Gay, Steffen, Gern, James, Haahtela

Journal:

Journal of Allergy and Clinical Immunology

Year:

2016

Language:

english

File:

PDF, 269 KB

english, 2016

2

Metabolic switch induced by Cimicifuga racemosa extract prevents mitochondrial damage and oxidative cell death

Rabenau, Malena, Unger, Matthias, Drewe, Jürgen, Culmsee, Carsten

Journal:

Year:

2018

Language:

english

File:

PDF, 995 KB

english, 2018

3

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

Alexander Seiler, Manuela Schneider, Heidi Förster, Stephan Roth, Eva K. Wirth, Carsten Culmsee, Nikolaus Plesnila, Elisabeth Kremmer, Olof Rådmark, Wolfgang Wurst, Georg W. Bornkamm, Ulrich Schweizer

Journal:

Cell Metabolism

Year:

2008

Language:

english

File:

PDF, 1.74 MB

english, 2008

4

Targeting the p53 pathway to protect the neonatal ischemic brain

Cora H. Nijboer, Cobi J. Heijnen, Michael A. van der Kooij, Jitske Zijlstra, Cindy T.J. van Velthoven, Carsten Culmsee, Frank van Bel, Henrik Hagberg, Annemieke Kavelaars

Journal:

Annals of Neurology

Year:

2011

Language:

english

File:

PDF, 977 KB

english, 2011

5

Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer

Sabine Boeckle, Katharina von Gersdorff, Silke van der Piepen, Carsten Culmsee, Ernst Wagner, Manfred Ogris

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 248 KB

english, 2004

6

Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA delivery

Peter J. Tarcha, Jaroslav Pelisek, Thomas Merdan, Jan Waters, Kent Cheung, Katharina von Gersdorff, Carsten Culmsee, Ernst Wagner

Journal:

Year:

2007

Language:

english

File:

PDF, 315 KB

english, 2007

7

Roles of Nuclear Factor κB in Neuronal Survival and Plasticity

Mark P. Mattson, Carsten Culmsee, ZaiFang Yu, Simonetta Camandola

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 323 KB

english, 2000

8

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β-peptide

Carsten Culmsee, Xiaoxiang Zhu, Qian-Sheng Yu, Sic L. Chan, Simonetta Camandola, Zhihong Guo, Nigel H. Greig, Mark P. Mattson

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 736 KB

english, 2001

9

p75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones

Nguyen Truc Bui, Hans-Georg König, Carsten Culmsee, Elke Bauerbach, Monika Poppe, Josef Krieglstein, Jochen H. M. Prehn

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 469 KB

english, 2002

10

Apoptotic and antiapoptotic mechanisms in stroke

Mark P. Mattson, Carsten Culmsee, Zai Fang Yu

Journal:

Cell and Tissue Research

Year:

2000

Language:

english

File:

PDF, 535 KB

english, 2000

11

Cellular and Molecular Mechanisms Underlying Perturbed Energy Metabolism and Neuronal Degeneration in Alzheimer's and Parkinson's Diseases

MARK P. MATTSON, WARD A. PEDERSEN, WENZHEN DUAN, CARSTEN CULMSEE, SIMONETTA CAMANDOLA

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 8.41 MB

english, 1999

12

Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies. International Symposium on Neurodegeneration and Neuroprotection

Culmsee, Carsten, Krieglstein, Josef

Journal:

Year:

2007

Language:

english

File:

PDF, 183 KB

english, 2007

13

Stimulation of ??2-Adrenoceptors Inhibits Apoptosis in Rat Brain After Transient Forebrain Ischemia

Zhu, Yuan, Culmsee, Carsten, Semkova, Irina, Krieglstein, Josef

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1998

Language:

english

File:

PDF, 1.17 MB

english, 1998

14

Neuroprotection by Estrogens in a Mouse Model of Focal Cerebral Ischemia and in Cultured Neurons: Evidence for a Receptor-Independent Antioxidative Mechanism

Culmsee, Carsten, Vedder, Helmut, Ravati, Alexander, Junker, Vera, Otto, D??rte, Ahlemeyer, Barbara, Krieg, J??rgen-Christian, Krieglstein, Josef

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1999

Language:

english

File:

PDF, 936 KB

english, 1999

15

Evidence for the Involvement of Par-4 in Ischemic Neuron Cell Death

Culmsee, Carsten, Zhu, Yuan, Krieglstein, Josef, Mattson, Mark P.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2001

Language:

english

File:

PDF, 4.22 MB

english, 2001

16

Nuclear Translocation of Apoptosis-Inducing Factor After Focal Cerebral Ischemia

Plesnila, Nikolaus, Zhu, Changlian, Culmsee, Carsten, Gr??ger, Moritz, Moskowitz, Michael A., Blomgren, Klas

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2004

Language:

english

File:

PDF, 2.05 MB

english, 2004

17

The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function

Weiming Fu, Michael Killen, Carsten Culmsee, Sonu Dhar, Tej K. Pandita, Mark P. Mattson

Journal:

Journal of Molecular Neuroscience

Year:

2000

Language:

english

File:

PDF, 573 KB

english, 2000

18

AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation

Carsten Culmsee, Jennifer Monnig, Bruce E. Kemp, Mark P. Mattson

Journal:

Journal of Molecular Neuroscience

Year:

2001

Language:

english

File:

PDF, 484 KB

english, 2001

19

Aberrant stress response associated with severe hypoglycemia in a transgenic mouse model of Alzheimer’s disease

Ward A. Pedersen, Carsten Culmsee, Dana Ziegler, James P. Herman, Mark P. Mattson

Journal:

Journal of Molecular Neuroscience

Year:

1999

Language:

english

File:

PDF, 144 KB

english, 1999

20

Proteomic Analysis Reveals Differences in Protein Expression in Spheroid versus Monolayer Cultures of Low-Passage Colon Carcinoma Cells

Gaedtke, Lars, Thoenes, Lilja, Culmsee, Carsten, Mayer, Barbara, Wagner, Ernst

Journal:

Journal of Proteome Research

Year:

2007

Language:

english

File:

PDF, 563 KB

english, 2007

21

Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: A potential therapeutic strategy for inhibition of tumor angiogenesis

Carsten Culmsee, Edith Gasser, Sabine Hansen, Joerg-Christian Tonn, Ernst Wagner, Roland Goldbrunner

Journal:

Year:

2006

Language:

english

File:

PDF, 633 KB

english, 2006

22

Enantio-selective effects of clenbuterol in cultured neurons and astrocytes, and in a mouse model of cerebral ischemia

Carsten Culmsee, Vera Junker, Serge Thal, Wolfram Kremers, Sandra Maier, Harald Jörn Schneider, Nikolaus Plesnila, Josef Krieglstein

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 810 KB

english, 2007

23

Stimulation of 5-HT1A receptors reduces apoptosis after transient forebrain ischemia in the rat

Christine Schaper, Yuan Zhu, Maria Kouklei, Carsten Culmsee, Josef Krieglstein

Journal:

Year:

2000

Language:

english

File:

PDF, 1.35 MB

english, 2000

24

Stimulation of β-adrenoceptors activates astrocytes and provides neuroprotection

Vera Junker, Andreas Becker, Ricarda Hühne, Marat Zembatov, Alexander Ravati, Carsten Culmsee, Josef Krieglstein

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 794 KB

english, 2002

25

Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats

Alexander Ravati, Vera Junker, Maria Kouklei, Barbara Ahlemeyer, Carsten Culmsee, Josef Krieglstein

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 1.19 MB

english, 1999

26

Clenbuterol induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage

Carsten Culmsee, Ralf K Stumm, Martin K.-H Schäfer, Eberhard Weihe, Josef Krieglstein

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 1.44 MB

english, 1999

27

Activation of KCNN3/SK3/KCa2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia

Amalia M. Dolga, Till Letsche, Maike Gold, Nunzianna Doti, Michael Bacher, Nipavan Chiamvimonvat, Richard Dodel, Carsten Culmsee

Journal:

Year:

2012

Language:

english

File:

PDF, 1.53 MB

english, 2012

28

Corticotropin-Releasing Hormone Protects Neurons against Insults Relevant to the Pathogenesis of Alzheimer's Disease

Ward A. Pedersen, Deanna McCullers, Carsten Culmsee, Norman J. Haughey, James P. Herman, Mark P. Mattson

Journal:

Neurobiology of Disease

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

29

Presenilin-1 Mutations Sensitize Neurons to DNA Damage-Induced Death by a Mechanism Involving Perturbed Calcium Homeostasis and Activation of Calpains and Caspase-12

Sic L. Chan, Carsten Culmsee, Norman Haughey, Wolfram Klapper, Mark P. Mattson

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 732 KB

english, 2002

30

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death

Julia Grohm, Nikolaus Plesnila, Carsten Culmsee

Journal:

Brain, Behavior, and Immunity

Year:

2010

Language:

english

File:

PDF, 668 KB

english, 2010

31

p53 in neuronal apoptosis

Carsten Culmsee, Mark P. Mattson

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 1017 KB

english, 2005

32

The tyrosine phosphatase inhibitor orthovanadate mimics NGF-induced neuroprotective signaling in rat hippocampal neurons

Norbert Gerling, Carsten Culmsee, Susanne Klumpp, Josef Krieglstein

Journal:

Neurochemistry International

Year:

2004

Language:

english

File:

PDF, 735 KB

english, 2004

33

Bone marrow stromal cells mediate protection through stimulation of PI3-K/Akt and MAPK signaling in neurons

Nicola B. Isele, Hea-Sook Lee, Stefan Landshamer, Andreas Straube, Claudio S. Padovan, Nikolaus Plesnila, Carsten Culmsee

Journal:

Neurochemistry International

Year:

2007

Language:

english

File:

PDF, 800 KB

english, 2007

34

Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity

Carsten Culmsee, Subbarao Bondada, Mark P. Mattson

Journal:

Molecular Brain Research

Year:

2001

Language:

english

File:

PDF, 853 KB

english, 2001

35

Egr-1 Regulates Expression of the Glial Scar Component Phosphacan in Astrocytes after Experimental Stroke

Heike Beck, Matthias Semisch, Carsten Culmsee, Nikolaus Plesnila, Antonis K. Hatzopoulos

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 4.39 MB

english, 2008

36

Causal Role of Apoptosis-Inducing Factor for Neuronal Cell Death Following Traumatic Brain Injury

Jennifer E. Slemmer, Changlian Zhu, Stefan Landshamer, Raimund Trabold, Julia Grohm, Ardavan Ardeshiri, Ernst Wagner, Marva I. Sweeney, Klas Blomgren, Carsten Culmsee, John T. Weber, Nikolaus Plesnila

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 1.38 MB

english, 2008

37

Statins — increasing or reducing the risk of Parkinson's disease?

Amalia M. Dolga, Carsten Culmsee, Lonneke de Lau, Yaroslav Winter, Wolfgang H. Oertel, Paul G.M. Luiten, Ulrich L.M. Eisel

Journal:

Experimental Neurology

Year:

2011

Language:

english

File:

PDF, 153 KB

english, 2011

38

P1-127: Lovastatin mediatesin vivo neuroprotection against NMDA-induced excitotoxicity

Amalia M. Dolga, Ivica Granic, Ingrid M. Nijholt, Carsten Culmsee, Paul G.M. Luiten, Ulrich L.M. Eisel

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

39

Mechanisms of neuronal degeneration after ischemic stroke – Emerging targets for novel therapeutic strategies

Carsten Culmsee, Josef Krieglstein

Journal:

Drug Discovery Today: Disease Mechanisms

Year:

2005

Language:

english

File:

PDF, 364 KB

english, 2005

40

Emerging pharmacotherapeutic strategies for the treatment of ischemic stroke

Carsten Culmsee, Josef Krieglstein

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2006

Language:

english

File:

PDF, 492 KB

english, 2006

41

Lubeluzole protects hippocampal neurons from excitotoxicity in vitro and reduces brain damage caused by ischemia

Carsten Culmsee, Vera Junker, Philipp Wolz, Irina Semkova, Josef Krieglstein

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 533 KB

english, 1998

42

Novel p53 Inactivators with Neuroprotective Action: Syntheses and Pharmacological Evaluation of 2-Imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-Imino-2,3,4,5,6,7-hexahydrobenzoxazole Derivatives ⊥

Zhu, Xiaoxiang, Yu, Qian-sheng, Cutler, Roy G., Culmsee, Carsten W., Holloway, Harold W., Lahiri, Debomoy K., Mattson, Mark P., Greig, Nigel H.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 196 KB

english, 2002

43

Mitochondrial pathways of neuronal cell death as therapeutic targets in neurological diseases

Culmsee, Carsten

Journal:

Pharmacological Reports

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

44

Mitoprotection is neuroprotection – Novel targets and therapeutics

Culmsee, Carsten

Journal:

Pharmacological Reports

Year:

2013

Language:

english

File:

PDF, 44 KB

english, 2013

45

Oxidative stress and neurodegeneration

White, Anthony, Culmsee, Carsten, Beart, Philip

Journal:

Neurochemistry International

Year:

2013

Language:

english

File:

PDF, 104 KB

english, 2013

46

Trifluoperazine rescues human dopaminergic cells from wild-type α-synuclein-induced toxicity

Höllerhage, Matthias, Goebel, Joachim N., de Andrade, Anderson, Hildebrandt, Tobias, Dolga, Amalia, Culmsee, Carsten, Oertel, Wolfgang H., Hengerer, Bastian, Höglinger, Günter U.

Journal:

Neurobiology of Aging

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

47

ATP dependent inhibition of cytochrome c oxidase results in decreased ROS production

Ramzan, Rabia, Weber, Petra, Schaper, Andreas K., Rhiel, Annika, Chillappagari, Shashi, Dolga, Amalia, Culmsee, Carsten, Vogt, Sebastian

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2014

Language:

english

File:

PDF, 63 KB

english, 2014

48

N -Acyl Derivatives of 4-Phenoxyaniline as Neuroprotective Agents

Barho, Marlene T., Oppermann, Sina, Schrader, Florian C., Degenhardt, Inga, Elsässer, Katharina, Wegscheid-Gerlach, Christof, Culmsee, Carsten, Schlitzer, Martin

Journal:

Year:

2014

Language:

english

File:

PDF, 55 KB

english, 2014

49

Pifithrin-α provides neuroprotective effects at the level of mitochondria independently of p53 inhibition

Neitemeier, Sandra, Ganjam, Goutham K., Diemert, Sebastian, Culmsee, Carsten

Journal:

Year:

2014

Language:

english

File:

PDF, 2.74 MB

english, 2014

50

Central Inhibition of IKKβ/NF-κB Signaling Attenuates High-Fat Diet–Induced Obesity and Glucose Intolerance

Benzler, Jonas, Ganjam, Goutham K., Pretz, Dominik, Oelkrug, Rebecca, Koch, Christiane E., Legler, Karen, Stöhr, Sigrid, Culmsee, Carsten, Williams, Lynda M., Tups, Alexander

Journal:

Year:

2015

Language:

english

File:

PDF, 2.72 MB

english, 2015